Pharmacology Update

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Chapter I Introduction Pages 7-20


1. You should always _____ when you are giving meds: don't do it out of habit.

  a. re-check

  b. think

  c. wash hands

  d. call the pharmacy


2. By preventing errors, the nurse will have the opportunity to perform patient

  a. teaching

  b. supervision

  c. billing

  d. procedures


3. GI problems and circulatory problems can interfere with the ________ of the drug.

  a. absorption

  b. penetration

  c. cost

  d. distribution

  e. excretion


4. The fate of the drug refers to the manner in which the drug is:

  a. excreted

  b. absorbed

  c. distributed

  d. used by the body


5. "Most Common" gastrointestinal side effects of most drugs include:

  a. diarrhea & dystonia

  b. nausea & drowsiness

  c. diarrhea & dysphagia

  d. nausea & rashes

  e. diarrhea & constipation


6. An adverse reaction to a drug is an undesirable and usually ______response.

  a. expected

  b. unanticipated

  c. mild

  d. allergic

  e. fatal


7. _________ is one category of drugs likely to cause allergic reactions.

  a. diuretics

  b. antibiotics

  c. insulin

  d. digoxin

  e. antiemetics


8. Vaccines may cause allergic reactions in those who have ________ sensitivity.

  a. antibiotics

  b. seafood

  c. egg

  d. meat

  e. pork


9. _______ is an acute medical emergency requiring prompt attention.

  a. CPR

  b. drug interaction

  c. anaphylaxis

  d. immunologic reaction


10. Narcotics may cause nonimmunologic reactions, usually those of _______.

  a. hypertension

  b. anaphylaxis

  c. urticaria

  d. bronchospasm


Chapter II Pharmacology Update (antibiotics) Pages 21-34


11. Zyvox is the first antibiotics in a new class of antibiotics called:

  a. penicillins

  b. flouroqinolones

  c. antifungals

  d. oxazolidinones


12. Lorabid is a broad-spectrum oral antibiotic used to treat ______ infections.

  a. bone

  b. gastrointestinal

  c. joint

  d. skin

  e. brain


13. Cefepime is contraindicated in patients who have had immediate hypersensitivity reactions to:

  a. erythromycin

  b. penicillin

  c. Zeneca

  d. quinolones


14. Meropenem has been initially approved for ______ infections.

  a. respiratory

  b. intra-abdominal

  c. fungal

  d. gnorrhea


15. Levaquin is the first once-a-day antibiotic proven effective against:

  a. acute maxillary sinusitis

  b. chronic meningitis

  c. N. gonorrhea


16. There is up to 98% decreased absorption of Levaquin when given with:

  a. iron prepartions

  b. warfarin

  c. theophylline

  d. penicillin


17. Sparfloxacin (Zagam) is contraindicatecd in patients with:

  a. CHF

  b. tachycardia

  c. fungal infections

  d. Alzheimer's Disease


18. Grepafloxacin should be discontinued if the patient experiences rupture of a:

  a. vein

  b. artery

  c. joint

  d. ligament

  e. tendon


19. Trovan is the first agent ever approved for oral prophylactic use in

  a. hepatitis

  b. endocarditis

  c. lumbar punctures

  d. surgery


20. ____________ is used against life-threatening VREF bacteremia.

  a. Synercid

  b. Probenecid

  c. Raxar

  d. Trovan

  e. none of these


Chapter II Pharmacology Update (Cardiovascular) Pages 35-41


21. Verapamil is used for slowing arryhythmias such as

  a. V fibrillation

  b. artrial fibrillation

  c. heart block


22. Adenosine ______ works by slowing the initiation of the SA node

  a. conduction

  b. reentry

  c. impulses

  d. innervation

  e. rhythm


23. When administering adenosine, you must observe the cardiac monitor for:

  a. heart block

  b. tachycardia

  c. flutter

  d. fibrillation

  e. asystole


24. MgSo4 may be given prophylactically for the acute _____ patient.

  a. CHF

  b. fibrillation

  c. asystole

  d. MI

  e. bradycardia


25. Inocor is used for short-term management of

  a. CHF

  b. fibrillation

  c. asystole

  d. MI

  e. bradycardia


26. Cilostazol relieves symptoms of intermittent claudication by inhibiting:

  a. blood coagulation

  b. platelet aggregation

  c. vasospasm


27. Zeneca is the first of a new class of agents for treating

  a. heart block

  b. heartburn

  c. asthma

  d. cancer

  e. CHF


28. Zanamivir reduced the duration of major __________ symptoms by one to 2-1/2 days.

  a. asthma

  b. cold

  c. arthritis

  d. diarrhea

  e. influenza


Chapter II Pharmacology Update (Musculoskeletal) Pages 45-48


29. Zanaflex is the first new oral drug for muscle

  a. weakness

  b. rigidity

  c. injury

  d. spasticity

  e. atrophy


30. Celecoxib is indicated for relief of syptoms of

  a. Osteoarthritis

  b. cancer

  c. muscle spasm

  d. hepatitis


Chapter II Pharmacoloav Update (Oncoloav) Pages 49-55


31. The PRINCIPLE of chemotherapy is to administer the __________ tolerable drug dose.

  a. minimum

  b. maximum

  c. extreme

  d. best

  e. generally


32. These drugs have a greater ability to attack cells in the resting phase:

  a. antitumor antibiotics

  b. alkylating agents

  c. nitrosoureas


33. M.O.P.P. stands for ______ Oncovin, Procarbazine, and Prednisone.

  a. Maran

  b. Marinol

  c. Mabilone

  d. Marplan

  e. Nitrogen mustard


34. Docetaxel is indicated for patients with metastatic _________ cancer.

  a. bladder

  b. bone

  c. brain

  d. breast

  e. liver


35. Ontak is the first drug specifically indicated to treat recurrent

  a. CTCL

  b. CMV

  c. breast cancer

  d. Hodgkin's Disease


Chapter II PHARMACOLOGY Update (Neurological) Pages 56-65


36. Prozac interacts with many other drugs; carbamazepine, insulin, and

  a. antacids

  b. dilantin

  c. valium

  d. penicillin

  e. erythromycin


37. Methemoglobinemia has occured when an OTC vaginal cream was used to treat:

  a. yeast infections

  b. diaper rash

  c. sore throat


38. Optimal conscious sedation/anagesia is achieved when the patient:

  a. is unresponsive

  b. recalls entire procedure

  c. retains gag reflex


39. __________ is recommended as a replacement for diazepam for conscious sedation.

  a. flourazepam

  b. morphine

  c. chloral hydrate

  d. Midazolam


40. Managing _________ adequately during the first procedure, usually helps reduce the anxiety associated with future procedures.

  a. pain

  b. sedation

  c. anxiety

  d. nausea

  e. the family


41. The goal (of Narcan) is to reverse the _______ depressant effect of opioids.

  a. pain

  b. neurological

  c. slight

  d. severe

  e. respiratory


42. A ______ dose of nalmefene is usually enough to reverse most opioids.

  a. large

  b. multiple

  c. small

  d. single

  e. double


43. The person evaluating the response of the patient to the drugs, must ____ the person performing the procedure.

  a. always be

  b. supervise

  c. not be

  d. instruct

  e. none of these


44. The duration of the post-procedure recovery period may vary depending on the type and _______ of sedative/analgesia administered.

  a. administration

  b. amount

  c. function

  d. route

  e. none of these


Chapter II Pharmacoloav Update (Gastrointestinal) Pages 65-70


45. Prilosec is an anti-ulcer drug that is becoming more useful in treating severe:

  a. esophagitis

  b. duodenal ulcer

  c. stomach ulcer

  d. stomatitis


46. Lispro may improve postprandial gylcemic control by mimicking the body's natural rapid insulin output after

  a. an injection

  b. sleeping

  c. bedtime

  d. fasting

  e. a meal


47. Rosiglitazone increases sensitivity to insulin and decreases _______ glucose output.

  a. stomach

  b. hepatic

  c. intestinal

  d. pancreatic

  e. pharyngeal


48. Adverse reactions to Miglitol include: abdominal pain, diarrhea, and ______

  a. uticaria

  b. constipation

  c. flatulence

  d. hyperglycemia


49. Orlistat works by blocking _________ in the GI tract.

  a. fats

  b. proteins

  c. carbohydrates

  d. digestion

  e. water


50. Aciphex is indicated for long-term treatment of ________ disease.

  a. diarrhea

  b. Zollinger-Ellison

  c. Addison's

  d. gastric acid


Chapter II Pharmacology Update (Psvchotropics) Pastes 72-96


51. Remeron is particularly useful in reducing anxiety and _______ problems which often accompany depression.

  a. sexual

  b. sleep

  c. visual

  d. mania

  e. drowsiness


52. Wellbutrin is used to treat depression and recently has been found to relieve symptoms of

  a. gastritis

  b. tremors

  c. ADHD

  d. Anxiety

  e. constipation


53. MAOI's are usually contraindicated in asthma, CHF, and

  a. diabetes

  b. gastric ulcers

  c. alcholism

  d. Addison's disease


54. The most common side effects of Depakote are drwsiness and

  a. vomiting

  b. headache

  c. diarrhea

  d. anxiety

  e. nausea


55. Adderall is a drug containing mixed salts of a single-entity _____ product.

  a. magnesium

  b. amphetamine

  c. TCA

  d. MAO1

  e. benzodiazepine


56. At least _______ should elapse betwen discontinuing MAO1 therapy and initiating the use of tricyclics.

  a. ten days

  b. 21 days

  c. one week

  d. one month

  e. 14 days


57. BuSpar is often prescribed to people with _______ axiety disorder.

  a. pre-op

  b. alcohol withdrawal

  c. agitation

  d. generalized


58. Tranxene is used as an anti-anxiety drug and for ________.

  a. alcohol withdrawal

  b. pre-op anxiety

  c. generalized anxiety


59. Tybatram is used for an anti-anxiety drug for tension and

  a. pre-op anxiety

  b. alcohol withdrawal

  c. agitation

  d. generalized anxiety


60. Patients receiving antipsychotic drugs whould have an evaluation of:

  a. thyroid tests

  b. liver function tests

  c. brain scan

  d. liver scan


61. Serentil has generally _______ side effects, with milder hypotensive effects than Thorazine.

  a. more severe

  b. CNS

  c. sedating

  d. fewer

  e. more


62. Compazine is more often used as an antiemetic;can be used for _____.

  a. diarrhea

  b. constipation

  c. sedation

  d. sleep

  e. antacid


63. Pimozide works by blocking _______ receptors and takes about two weeks to work.

  a. ACTH

  b. neural

  c. dopamine

  d. brain

  e. serotonin


64. Risperdal is indicated for the management of _______ disorders.

  a. psychotic

  b. anxiety

  c. neurotic

  d. ADHD

  e. dissociative


65. Too much dopamine causes nerve impulses in the brain stem to be transmitted ________ than normal.

  a. faster

  b. slower


66. Extrapyramidal side effects, or adverse neurological effects may occur during the _____ phase of drug therapy.

  a. involuntary

  b. early

  c. middle

  d. late

  e. voluntary


67. This side effect (Parkinsonism) involves motor retardation or

  a. nausea

  b. akinesia

  c. dry mouth

  d. vomiting

  e. blurred vision


68. Some symptoms of EPS include: fatigue, drowsiness, drooling, and

  a. dry mouth

  b. blurred vision

  c. mania

  d. weakness

  e. tremors


69. Inderal, used to treat hypertension, is also used to treat migraines and:

  a. psychosis

  b. diabetes

  c. bradycardia

  d. Parkinson's symptoms


Chapter III Pharmacology Update (Drug Abuse/Legal Issues) Pages 97-99


70. Trexan is administered to the person after total ______ from the narcotic.

  a. intoxication

  b. rehabilitation

  c. addiction

  d. detoxification


71. The usual side effects of Timolol Eye Drops are: dyspepsia, hypotension,and:

  a. fatigue

  b. hypertension

  c. vomiting

  d. diarrhea


Chapter III Pharmacology Update (Oral Contraceptives) Pages 100-103


72. The "mini-pill" contains only progestin, it must be taken

  a. for 21 days

  b. every day

  c. after meals

  d. twice daily


73. Most combination contraceptives will begin on the first _______ after menses.

  a. Sunday

  b. Monday

  c. day

  d. evening

  e. cycle


74. "Plan B11 is the first dedicated _______ pill developed in the U.S. to prevent pregnancy after unprotected intercourse.

  a. estrogen-only

  b. progestin-only

  c. mini

  d. abortion


Chapter III Pharmacology Update (Hepatitis Update) Pages 104


75. The immunization (Heptavax-B) apparently has a higher rate of _____ if given in the deltoid for some unknown reason.

  a. potency

  b. nausea

  c. side effects

  d. rashes

  e. effectiveness


Chapter III Pharmacology Update (HIV/AIDS) Pages 105-110


76. Usually ____ is the first drug used to treat the HIV viral infection.

  a. Retrovir

  b. Saquinavir

  c. AZT

  d. ddI

  e. ddC


77. Coadministration of ritonavir and non-sedating _____ may produce life-threatening situations.

  a. anti-virals

  b. cough syrups

  c. OTC drugs

  d. antihistamines


78. The patient must take ______ capsules of amprenavir per dose.

  a. two

  b. four

  c. six

  d. eight

  e. ten


79. Amprenavir may be taken with or without food, but avoid taking it with a ____ meal.

  a. high protein

  b. low carbohydrate

  c. low-fat

  d. high-fat


Chapter III Pharmacology Update (Elderly Drug Therapy) Pages 111-127


80. The main factors that affect drug therapy in the elderly are _____ gastric emptying time, and rise in gastric juices.

  a. decreased

  b. increase


81. In aging, there is diminished renal blood flow, and ________.

  a. reabsorption

  b. increased filtration

  c. increased secretion


82. A condtion under which the need for calcium rises: _____ diet.

  a. low sugar

  b. low protein

  c. low phosphate

  d. high sodium


83. It's easy to miss adverse drug reactions, because many reactions such as confusion, _______, or constipation, are common (in the elderly).

  a. falling

  b. alcoholism

  c. dizziness

  d. flatulence


84. The 300 mg dose (of phenytoin) may produce such effects as sleeplessness, confusion, and nystagmus in a geriatric patient with _______.

  a. diabetes

  b. hypoalbuminemia

  c. hyperbilirubinemia

  d. none of these


85. With age, a drug or active metabolites may remain in the body longer: repeated dosing may result in significant __________ of the drug.

  a. elimination

  b. accumulation

  c. detoxification

  d. deactivation


86. In older patients, these drugs (valium, etc.) will remain in the body longer and can cause daytime sedation or ______ in the morning.

  a. excitement

  b. energy

  c. lethargy

  d. hunger

  e. anger


87. The following drugs require dosage adjustment for patients with diminished renal function: allopurinol (Zyloprim) and:

  a. aspirin

  b. Lanoxin

  c. valium

  d. tylenol


88. Demerol is another drug that poses risks to older patients with renal impairment: toxicity is caused by an active metabolite called

  a. meperidine

  b. hydromorphone

  c. neurotoxin

  d. normeperidine


89. Older adults appear to be more sensitive to ________ adverse drug reactions.

  a. anticholinergic

  b. sympathomimetic

  c. serotonin

  d. hepatic


90. A common problem your history may uncover is the use of ______ medications

  a. anagesic

  b. illegal

  c. multiple

  d. outdated

  e. OTC


91. Often what determines the effect of a drug is the ratio between total body ______ and fat.

  a. water

  b. blood volume

  c. composition

  d. enzymes


92. As many as ____ of elderly patients do not administer their medications as prescribed.

  a. 5%

  b. 15%

  c. 20%

  d. 30%

  e. 40%


93. The primary reasons for nonadherence to drug treatment in the older patient are poor communication with _________ and declining cognitive function.

  a. their family

  b. their pharmacist

  c. their doctor

  d. health professionals


Appendix A Pharmacology Update Pages 128


94. The drug formerly used to treat gastroesophageal reflux disease will no longer be marketed in the U.S.

  a. Rezulin

  b. Pin-X

  c. Propulsid

  d. Doxicin

  e. Acetylate


95. Because the eggs are easily transmitted, even through the _____, pinworms can occur in the cleanest of households.

  a. air

  b. bed clothes

  c. hair

  d. hands

  e. fingernails


Appendix B Pharmacology Update Pages 129-132


96. Factors contributing to drug polymorphism among various ethnic groups can be loosely categorized as environmentl, cultural, and ________.

  a. biological

  b. genetic

  c. social

  d. historical


97. Generally, drugs that are titrated for individual tolerance or efficacy simutaneously adjust for _______.

  a. cultures

  b. race

  c. social factors

  d. effectiveness


98. If only one drug is used, blacks respond better to diuretics than to beta blockers and __________.

  a. antidepressants

  b. benzodiazepines

  c. ACE inhibitors

  d. insulin


Appendix C Pharmacology Update Pages 133


99. ________ has recently been shown to reduce the effectiveness of certainHIV anti-viral drugs.

  a. ephedra

  b. ginseng

  c. insulin

  d. St. John's Wort


100. This herb, ______ should not be used by persons with diabetes.

  a. ginseng

  b. ephedra

  c. St John's Wort

  d. insulin

  e. soy